Researchers work to unravel cancer biology across the animal world

Less than 5% of zoo elephant deaths are caused by cancer, while 11% to 25% percent of humans succumb to cancer, but elephants have extra copies of the p53 gene, which plays a role in stopping proliferation of faulty DNA and might function differently in elephants than in humans. Researchers are working to unravel Peto’s paradox — a principle that acknowledges that larger, longer-lived animals should experience higher rates of cancer than small, short-lived species — as well as questions about why some dog breeds are more susceptible to cancers than others. The answers could inform treatment of cancer across species. Newsweek (10/8), The New York Times (free-article access for SmartBrief readers) (10/8)

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